Abnormal fat buildup in the brain could accelerate Alzheimer’s

October 2015   Comments

An accumulation of fat droplets in the brains of patients who died from Alzheimer’s disease has been discovered by University of Montreal Hospital Research Centre researchers. The brains of nine former Alzheimer’s patients had significantly more triglycerides enriched with specific fatty acids than five healthy brains. While these fatty acids normally build up slowly, genes that predispose people to Alzheimer’s significantly accelerate the process. Pharmacological inhibitors of the enzyme that produces these fatty acids, which other researchers are testing for metabolic diseases, could be effective in treating Alzheimer’s.

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